null

SMILES COc1ccc2NC(=O)[C@@]3(C[C@H]3c3ccc4c(\C=C\c5ccc(CN(C)C)cc5)n[nH]c4c3)c2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50044656   

TargetAurora kinase B(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM50044656(CHEMBL3353348 | US10358436, Example A35 | US990780...)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K939WHUS Patent
TargetAurora kinase B(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM50044656(CHEMBL3353348 | US10358436, Example A35 | US990780...)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM50044656(CHEMBL3353348 | US10358436, Example A35 | US990780...)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM50044656(CHEMBL3353348 | US10358436, Example A35 | US990780...)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of AURKB (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V9WPubMed