null

SMILES Sc1cccc2cc(cnc12)C(=O)NCCc1nccs1

InChI Key InChIKey=MYNGHZGMRXNEEH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 224012   

TargetBRISC and BRCA1-A complex member 1/BRISC and BRCA1-A complex member 2/BRISC complex subunit Abraxas 2/Lys-63-specific deubiquitinase BRCC36(Homo sapiens (Human))
California Institute of Technology

LigandBDBM224012(Capzimin | US10005735, Compound 12)copy SMILEScopy InChI

Affinity DataIC50: 2.30E+3nMAssay Description:BRCC36 activity was measured using 1 nM purified BRISC complex and 80 nM di-ubiquitin substrate DiUbK63TAMRA (UF-310, Boston Biochem). TAMRA fluoresc...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D0BPubMed