null

SMILES CO[C@H]1CC[C@@]2(Cc3ccc(cc3C22N=C(C)C(N)=N2)-c2cncc(c2)C#CC)CC1

InChI Key InChIKey=WKDNQONLGXOZRG-HDVKRFLQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50393099   

TargetBeta-secretase 1 [1-460](Homo sapiens (Human))
University of Tennessee Health Science Center

LigandPNGBDBM50393099(CHEMBL2152914 | US10231967, Example 122 | US991898...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:The enzyme (truncated form) was diluted to 6 μg/mL (stock 1.3 mg/mL) and the substrate (Europium)CEVNLDAEFK(Qsy7) to 200 nM (stock 120 μM) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5WP7US Patent
TargetBeta-secretase 1 [1-460](Homo sapiens (Human))
University of Tennessee Health Science Center

LigandPNGBDBM50393099(CHEMBL2152914 | US10231967, Example 122 | US991898...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:The enzyme (truncated form) was diluted to 6 μg/mL (stock 1.3 mg/mL) and the substrate (Europium)CEVNLDAEFK(Qsy7) to 200 nM (stock 120 μM) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5WP7US Patent
TargetBeta-secretase 1 [1-460](Homo sapiens (Human))
University of Tennessee Health Science Center

LigandPNGBDBM50393099(CHEMBL2152914 | US10231967, Example 122 | US991898...)copy SMILEScopy InChI
Affinity DataIC50: 7.72E+3nMAssay Description:The enzyme (truncated form) was diluted to 6 μg/mL (stock 1.3 mg/mL) and the substrate (Europium)CEVNLDAEFK(Qsy7) to 200 nM (stock 120 μM) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5WP7US Patent