null

SMILES Sc1cccc2cc(cnc12)C(=O)NCCc1nccs1

InChI Key InChIKey=MYNGHZGMRXNEEH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 224012   

TargetCOP9 signalosome complex subunit 5(Homo sapiens (Human))
California Institute of Technology

LigandPNGBDBM224012(Capzimin | US10005735, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMpH: 7.5Assay Description:Csn5 activity was measured using purified CSN complex and the fluorescent substrate OGNedd8–SCFSkp2, in which a unique cysteine engineered into ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D0BPubMed
TargetCOP9 signalosome complex subunit 5(Homo sapiens (Human))
California Institute of Technology

LigandPNGBDBM224012(Capzimin | US10005735, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3V09US Patent