null
SMILES CCN1CCC(CC1)n1nc(Cc2cccc3ccccc23)c2c(N)ncnc12
InChI Key InChIKey=BSGWEWBSWAVORO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50345717
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington.
Curated by ChEMBL
University of Washington.
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of Toxoplasma gondii recombinant N-terminal hexahistidine tagged CDPK1 expressed in Escherichia coli using syntide-2 as substrate after 90...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington.
Curated by ChEMBL
University of Washington.
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington.
Curated by ChEMBL
University of Washington.
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington.
Curated by ChEMBL
University of Washington.
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair