null

SMILES NCCc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=FXNSVEQMUYPYJS-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer. 7 PDB IDs contain this monomer as substructures. 9 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

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Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 10861   

TargetCarbonic anhydrase 4(Homo sapiens (Human))
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  349nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862JPHPubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  2.44E+3nMAssay Description:Inhibition of bovine CA4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z761VPubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  2.45E+3nMAssay Description:Inhibition of bovine carbonic anhydrase IV (CAIV)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GC9PubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  2.45E+3nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1XXCPubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  2.45E+3nMAssay Description:Inhibitory activity against bovine lung microsomes carbonic anhydrase isozyme IV (bCA IV).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67HMKPubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  2.45E+3nMAssay Description:Inhibitory activity against bovine carbonic anhydrase isozyme IV isolated from bovine lung microsomes, by esterase assay method.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6KXVPubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  2.45E+3nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (bCAIV)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9R6QPubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  2.45E+3nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806T7PubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of cloned isozyme, human carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GJQPubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+3nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N29XN9PubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of bovine carbonic anhydrase IV from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J6MPubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+3nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FDPPubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)copy SMILEScopy InChI
Affinity DataKi:  3.57E+3nMAssay Description:Inhibitory activity against human carbonic anhydrase IV (hCAIV)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9R6QPubMed