null

SMILES CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1

InChI Key InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 10887   

TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Sup£rieure de Chimie de Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Inhibition of human recombinant CA5A after 15 mins by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4D3DPubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Sup£rieure de Chimie de Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Inhibition of human carbonic anhydrase 5AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28916QGPubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Sup£rieure de Chimie de Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Inhibition of human recombinant CA5A by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6M96PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Sup£rieure de Chimie de Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Inhibition of human recombinant CA5A by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959JF0PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Sup£rieure de Chimie de Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Inhibition of full length human carbonic anhydrase 5a preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K7QPubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Sup£rieure de Chimie de Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Inhibition of human recombinant CA5A mitochondrial isoform by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TF6PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Sup£rieure de Chimie de Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902200PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Sup£rieure de Chimie de Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6GKTPubMed
TargetCarbonic anhydrase 5A, mitochondrial(Mus musculus (mouse))
Universita degli Studi di Firenze

LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FDPPubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Sup£rieure de Chimie de Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  63nM ΔG°:  -9.82kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2SF1PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Sup£rieure de Chimie de Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319ZFQPubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Sup£rieure de Chimie de Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of full length human recombinant mitochondrial carbonic anhydrase 5A pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0NK7PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Sup£rieure de Chimie de Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKd:  25.4nMAssay Description:Inhibition of human carbonic anhydrase 5AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BWNPubMed