null
SMILES Fc1cc(NCC23CCCN2CCC3)c(Cl)cc1S(=O)(=O)Nc1nccs1
InChI Key InChIKey=XFWKBJBSEOZBRA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50240277
TargetCytochrome P450 3A4(Homo sapiens (Human))
Department of Discovery Chemistry Merck& Co.
Curated by ChEMBL
Department of Discovery Chemistry Merck& Co.
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam/testosterone as substrate after 30 mins in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Department of Discovery Chemistry Merck& Co.
Curated by ChEMBL
Department of Discovery Chemistry Merck& Co.
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 expressed in baculovirus-infected insect cells using 7-Benzoyloxy-4-trifluoromethyl coumarin substrate in pres...More data for this Ligand-Target Pair