null

SMILES Cn1cc(cn1)-c1ccc2ncc3ccc(=O)n(-c4ccc5CCN(C(=O)C=C)c5c4)c3c2c1

InChI Key InChIKey=RTRNJQOBEOISFQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50245587   

TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50245587(CHEMBL4077064 | US10000483, Compound II-4)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8W63US Patent
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50245587(CHEMBL4077064 | US10000483, Compound II-4)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant full length His-tagged human BMX expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4T51PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50245587(CHEMBL4077064 | US10000483, Compound II-4)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged BMX expressed in baculovirus infected Sf9 insect cells using poly (Glu,Tyr)4:1 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5HCKPubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50245587(CHEMBL4077064 | US10000483, Compound II-4)copy SMILEScopy InChI
Affinity DataIC50: 6.73nMAssay Description:Purified BMX was mixed with substrate (FAK or Bmxtides), kinase buffer (final 20 mM HEPES, pH 7.5, 10 mM MgCl2, 20 mM β-glycerophosphate, 1 mM d...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8W63US Patent