null

SMILES CC1=CCC(=C\C1=N\C(=O)C1=CC=C\C(C1)=N/C(=O)/N=C1/CC(=CC=C1)C(=O)\N=C1\CC(=CC=C1C)C(=O)\N=C1/CC=C(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O)C(=O)\N=C1/CC=C(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O

InChI Key InChIKey=VTCUUTNDNRAQSK-NCNWUEASSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50179360   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Competitive inhibition of human NPP1 expressed in African green monkey COS7 cells using ATP as substrate after 20 mins by Michaelis-Menten plot analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ928TPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)copy SMILEScopy InChI
Affinity DataIC50: 8.67E+3nMAssay Description:Inhibition of human full length NPP1 expressed in African green monkey COS7 cell membrane fraction using p-nitrophenyl-5'-thymidine monophosphate as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9RXTPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)copy SMILEScopy InChI
Affinity DataIC50: 8.67E+3nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells using p-nitrophenyl-5'-thymidine monophosphate as substrate preincubated for 5 to 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C20K3PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)copy SMILEScopy InChI
Affinity DataIC50: 8.67E+3nMAssay Description:Inhibition of NPP1 (unknown origin) using pNP-TMP as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CD9PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)copy SMILEScopy InChI
Affinity DataIC50: 8.67E+3nMAssay Description:Inhibition of human NPP1 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52SX7PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)copy SMILEScopy InChI
Affinity DataIC50: 7.77E+3nMAssay Description:Inhibition of human recombinant NPP1 expressed in COS-7 cell membrane at 100 uM using p-nitrophenyl thymidine monophosphate substrate incubated for 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HZZPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)copy SMILEScopy InChI
Affinity DataIC50: 7.77E+3nMAssay Description:Inhibition of human NPP1 transfected in COS7 cells using pNP-TMP as substrate incubated for 35 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3WFJPubMed