null
SMILES COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O
InChI Key InChIKey=HUFOZJXAKZVRNJ-UHFFFAOYSA-N
PDB links: 2 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 149404
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
BETTA PHARMACEUTICALS CO., LTD.
US Patent
BETTA PHARMACEUTICALS CO., LTD.
US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
BETTA PHARMACEUTICALS CO., LTD.
US Patent
BETTA PHARMACEUTICALS CO., LTD.
US Patent
Affinity DataKd: 1.40nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
BETTA PHARMACEUTICALS CO., LTD.
US Patent
BETTA PHARMACEUTICALS CO., LTD.
US Patent
Affinity DataIC50: 16.6nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
BETTA PHARMACEUTICALS CO., LTD.
US Patent
BETTA PHARMACEUTICALS CO., LTD.
US Patent
Affinity DataIC50: 1nMAssay Description:Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
BETTA PHARMACEUTICALS CO., LTD.
US Patent
BETTA PHARMACEUTICALS CO., LTD.
US Patent
Affinity DataIC50: 1nMAssay Description:Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...More data for this Ligand-Target Pair