null
SMILES C\C=C\C\C=C\CCC(=O)[C@H]1O[C@H]1C(N)=O
InChI Key InChIKey=GVEZIHKRYBHEFX-NQQPLRFYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50009248
Affinity DataIC50: 1.30E+4nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
TargetFatty acid synthase(Homo sapiens (Human))
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human FAS assessed as synthesis of long chain fatty acids from malonyl CoA after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetFatty acid synthase(Homo sapiens (Human))
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of FAS in human ZR-75-1 cells by spectrophotometryMore data for this Ligand-Target Pair
TargetFatty acid synthase(Homo sapiens (Human))
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of FASN in human A375 cellsMore data for this Ligand-Target Pair
TargetFatty acid synthase(Homo sapiens (Human))
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of FASMore data for this Ligand-Target Pair
TargetFatty acid synthase(Homo sapiens (Human))
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
Boehringer Ingelheim Pharma GmbH& Co. KG
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:Inhibition of fatty acid synthaseMore data for this Ligand-Target Pair