null

SMILES Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12

InChI Key InChIKey=FLVRDMUHUXVRET-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50038168   

TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Glaxo Wellcome S.p.A.

Curated by ChEMBL
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]glycine to glycine binding site, associated with the N-methyl-D-aspartate glutamate receptor 1 in crude synaptic membranes prepared...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5JBVPubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Glaxo Wellcome S.p.A.

Curated by ChEMBL
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HT2NJBPubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Glaxo Wellcome S.p.A.

Curated by ChEMBL
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ293MPubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Glaxo Wellcome S.p.A.

Curated by ChEMBL
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Compound was evaluated for its ability to displace [3H]-L-689,560 from rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1CMK
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Glaxo Wellcome S.p.A.

Curated by ChEMBL
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67G1JPubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Glaxo Wellcome S.p.A.

Curated by ChEMBL
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6Q8CPubMed