null
SMILES COc1cc(F)ccc1-c1cncc(CNC(=O)c2ccccn2)c1
InChI Key InChIKey=XEKZQVZQOZRWEJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50344260
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
AstraZeneca Pharmaceuticals
Curated by ChEMBL
AstraZeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 116nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
AstraZeneca Pharmaceuticals
Curated by ChEMBL
AstraZeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 673nMAssay Description:Antagonist activity at human NR2B expressed in HEK293 cells assessed as glutamate-induced changes in intracellular calcium concentrationMore data for this Ligand-Target Pair