null
SMILES Cn1cc(C2=C(C(=O)NC2=O)c2ccc(Cl)cc2Cl)c2ccccc12
InChI Key InChIKey=JCSGFHVFHSKIJH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 8296
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University of Cambridge
Curated by ChEMBL
University of Cambridge
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Competitive inhibition of full length recombinant human GSK-3alpha expressed in baculovirus infected insect Sf9 cells using GS-2 peptide as substrate...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University of Cambridge
Curated by ChEMBL
University of Cambridge
Curated by ChEMBL
Affinity DataKi: 9.10nM ΔG°: -10.9kcal/mole IC50: 34.3nMpH: 7.0 T: 2°CAssay Description:In vitro kinase inhibition assay using purified GSK-3 alpha from insect cells, was incubated at room temperature with substrate, and test compounds i...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University of Cambridge
Curated by ChEMBL
University of Cambridge
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of full length recombinant human GSK-3alpha expressed in baculovirus infected insect Sf9 cells using GS-2 peptide as substrate assessed as...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University of Cambridge
Curated by ChEMBL
University of Cambridge
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University of Cambridge
Curated by ChEMBL
University of Cambridge
Curated by ChEMBL
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar
In DepthDetails