null
SMILES C[C@@H](c1ccc(nc1)C(F)(F)F)n1nc(C#N)c2c1nc([nH]c2=O)C1CCC1c1ncc(cn1)C(F)F
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 484583
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Merck Sharp & Dohme Corp.
US Patent
Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 0.180nMAssay Description:Assays for PDE 1 through 11 were performed in parallel at room temperature in 384-well microtiter plates with an incubation volume of 20.2 μL. S...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Merck Sharp & Dohme Corp.
US Patent
Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 21.8nMAssay Description:Assays for PDE 1 through 11 were performed in parallel at room temperature in 384-well microtiter plates with an incubation volume of 20.2 μL. S...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Merck Sharp & Dohme Corp.
US Patent
Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 33.9nMAssay Description:Assays for PDE 1 through 11 were performed in parallel at room temperature in 384-well microtiter plates with an incubation volume of 20.2 μL. S...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Merck Sharp & Dohme Corp.
US Patent
Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 165nMAssay Description:Assays for PDE 1 through 11 were performed in parallel at room temperature in 384-well microtiter plates with an incubation volume of 20.2 μL. S...More data for this Ligand-Target Pair