null
SMILES CC(C)n1c(C)c(C(=O)NCc2c(C)cc(C)nc2O)c2ccccc12
InChI Key InChIKey=FIRTTWLRGQQVTR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50110363
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Constellation Pharmaceuticals, Inc.
Curated by ChEMBL
Constellation Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 159nMAssay Description:Inhibition of EZH2 (unknown origin) using biotinylated nucleosome, H3K27me3 activator and [3H]-SAM incubated for 60 mins by top-count based methodMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Constellation Pharmaceuticals, Inc.
Curated by ChEMBL
Constellation Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 512nMAssay Description:Inhibition of EZH2 Y641N mutant (unknown origin) using biotinylated nucleosome, H3K27me3 activator and [3H]-SAM incubated for 60 mins by top-count ba...More data for this Ligand-Target Pair