null
SMILES CN(C)c1ccc2cc(NC(=O)c3cnn4cccnc34)c(cc2n1)N1CCCCC1
InChI Key InChIKey=AHYTYKPDDJPJKK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50514923
Affinity DataKi: 26nMAssay Description:Inhibition of human recombinant full length His6-tagged IRAK4 expressed in baculovirus expression system using H-KKARFSRFAGSSPSQSSMVAR as substrate i...More data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of IRAK4 in human THP1-Xblue-MD2-CD14 cells assessed as reduction in LPS-induced NFkappaB transcription by measuring alkaline phosphatase ...More data for this Ligand-Target Pair