null
SMILES [H][C@@]12C[C@]([H])(C(=C/OC)\C(=O)OC)[C@]([H])(CC)CN1CC[C@]21Nc2cccc(OC)c2C1=O
InChI Key InChIKey=BAEJBRCYKACTAA-WGUOAFTMSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50474150
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Chiba University
Curated by ChEMBL
Chiba University
Curated by ChEMBL
Affinity DataKi: 79nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor kappa 1 using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataKi: 79nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 132nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 132nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Antagonist activity at mouse kappa opioid receptor-1 expressed in CHO cell membranes assessed as inhibition of U50,488H-induced [35S]GTPgammaS bindin...More data for this Ligand-Target Pair