null
SMILES [H][C@@]1(CC)CN2CCc3c([nH]c4cccc(OC)c34)[C@]2([H])C[C@]1([H])C(=C/OC)\C(=O)OC
InChI Key InChIKey=LELBFTMXCIIKKX-QVRQZEMUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50474152
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: 123nMAssay Description:Inhibition of kappa opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 198nMAssay Description:Displacement of [3H]U69,593 from human recombinant kappa opioid receptor expressed in rat RBL cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 231nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]U-69593 from kappa opoid receptor in Dunkin-Hartley guinea pig brain after 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor kappa 1 using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at mouse kappa opioid receptor-1 expressed in CHO cell membranes assessed as inhibition of U50,488H-induced [35S]GTPgammaS bindin...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig brain membranes by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair