null
SMILES FC(F)(F)c1cc(NC(=O)[C@H]2CC=C[C@H]3CCN(Cc4ccccc4)C(=O)[C@@H]23)ccc1Cl
InChI Key InChIKey=BSPPZJZWKVYWNH-DJPFJPOOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 214799
TargetKappa-type opioid receptor [K200A](Homo sapiens (Human))
University of North Carolina School of Medicine
University of North Carolina School of Medicine
Affinity DataKi: 180nM ΔG°: -9.19kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor [K200A](Homo sapiens (Human))
University of North Carolina School of Medicine
University of North Carolina School of Medicine
Affinity DataEC50: 80nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair