null
SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O
InChI Key InChIKey=OVVIBUHLQIYUEU-IWIISZHXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 214798
TargetKappa-type opioid receptor [Y320F](Homo sapiens (Human))
University of North Carolina School of Medicine
University of North Carolina School of Medicine
Affinity DataKi: 18nM ΔG°: -10.6kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor [Y320F](Homo sapiens (Human))
University of North Carolina School of Medicine
University of North Carolina School of Medicine
Affinity DataEC50: 76nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair