null
SMILES O=c1[nH]cnc2c(nccc12)-n1cc(cn1)C1CCN(CC2CCC2)CC1
InChI Key InChIKey=FQYVJQRHNLIPIK-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50513346
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataEC50: 9.10E+3nMAssay Description:Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 265nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 477nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 8.68E+3nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 121nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 564nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 248nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 4.21E+3nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair