null

SMILES OC(=O)c1ccnc(c1)C(O)=O

InChI Key InChIKey=MJIVRKPEXXHNJT-UHFFFAOYSA-N

PDB links: 16 PDB IDs match this monomer. 18 PDB IDs contain this monomer as substructures. 18 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26113   

TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+4nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8X6KPubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.46E+4nMAssay Description:Inhibition of KDM6B (unknown origin) expressed in Escherichia coli using H3 (21 to 44 residues) K27Me3-GGK-Biotin JMJD3 Cognate Ligand/10 uM alpha-ke...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84DRXPubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of KDM6B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0RBNPubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails