null

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(NC(=O)c3cc4ccccc4cn3)cc2)no1

InChI Key InChIKey=YRUDYNCGPZHXRB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50310628   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences Inc.

Curated by ChEMBL
LigandPNGBDBM50310628(AB-460 | CHEMBL1081509 | N-(4-(3-(5-tert-butylisox...)copy SMILEScopy InChI
Affinity DataKd:  8.5nMAssay Description:Binding affinity to CSF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1RVBPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50310628(AB-460 | CHEMBL1081509 | N-(4-(3-(5-tert-butylisox...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2H9VPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences Inc.

Curated by ChEMBL
LigandPNGBDBM50310628(AB-460 | CHEMBL1081509 | N-(4-(3-(5-tert-butylisox...)copy SMILEScopy InChI
Affinity DataKd:  8.5nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2H9VPubMed