null

SMILES CCOC(=O)N1CC\C(C1)=C/C#Cc1cccc(C)n1

InChI Key InChIKey=NDVDBJIRXMBDOD-VGOFMYFVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50529959   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529959(CHEMBL4551786)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]MPEP from human mGlu5 receptor expressed in CHO-TREx cell membranes after 60 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529959(CHEMBL4551786)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]MPEP from human mGlu5 receptor expressed in CHO-TREx cell membranes after 60 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529959(CHEMBL4551786)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as increased in calcium activated photo protein aequorin level...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529959(CHEMBL4551786)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in calcium activated photo protein aequorin le...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529959(CHEMBL4551786)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in calcium activated photo protein aequorin le...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529959(CHEMBL4551786)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529959(CHEMBL4551786)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529959(CHEMBL4551786)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as increased in calcium activated photo protein aequorin level...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed