null

SMILES CN(C)CCCc1cncc(CCc2cc(C)cc(N)n2)c1

InChI Key InChIKey=TUAXAWZDVAYXFN-UHFFFAOYSA-N

PDB links: 4 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 190668   

TargetNitric oxide synthase, endothelial(Rattus norvegicus)
Northwestern University

US Patent
LigandPNGBDBM190668(US10759791, Compound 14k | nNOS inhibitor, 6)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

US Patent
LigandPNGBDBM190668(US10759791, Compound 14k | nNOS inhibitor, 6)copy SMILEScopy InChI
Affinity DataKi:  1.66E+4nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

US Patent
LigandPNGBDBM190668(US10759791, Compound 14k | nNOS inhibitor, 6)copy SMILEScopy InChI
Affinity DataKi:  1.66E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli using L-arginine as substrate assessed as reduction in NO production measured for...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM190668(US10759791, Compound 14k | nNOS inhibitor, 6)copy SMILEScopy InChI
Affinity DataKi:  3.95E+4nMAssay Description:Inhibition of human recombinant eNOS expressed in Escherichia coli using L-arginine as substrate assessed as reduction in NO production measured for ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM190668(US10759791, Compound 14k | nNOS inhibitor, 6)copy SMILEScopy InChI
Affinity DataKi:  3.95E+4nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair