null
SMILES CC(C)[C@@H]1CN(CCN1c1ncc(c(n1)C(F)(F)F)C(C)(C)O)c1ccc(F)c(c1)S(C)(=O)=O
InChI Key InChIKey=HXOUVMGQDQYWNM-KRWDZBQOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50177018
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]TO901317 from LXRbeta ligand binding domain (unknown origin) after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Agonist activity at human LXRbeta ligand binding domain(155 to 460 residues) transfected in HEK293 cells after 16 hrs by Gal4-luciferase reporter gen...More data for this Ligand-Target Pair