null

SMILES Cc1nc(N=Nc2ccc(cc2S(O)(=O)=O)S(O)(=O)=O)c(COP(O)(O)=O)c(C=O)c1O

InChI Key InChIKey=PNFZSRRRZNXSMF-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 85043   

TargetP2X purinoceptor 4(Homo sapiens (Human))
Max-Planck Institute for Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)copy SMILEScopy InChI
Affinity DataKi:  27.5nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218351BPubMed
TargetP2X purinoceptor 4(RAT)
Max-Planck Institute for Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)copy SMILEScopy InChI
Affinity DataKi:  500nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218351BPubMed
TargetP2X purinoceptor 4(RAT)
Max-Planck Institute for Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of inward ion current elicited by ATP at rat P2X4 receptor (mutant type)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Max-Planck Institute for Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)copy SMILEScopy InChI
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of inward ion current elicited by ATP at human P2X4 receptor (mutant type)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2X purinoceptor 4(RAT)
Max-Planck Institute for Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 3 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0H71PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Max-Planck Institute for Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 4 (P2X4)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0H71PubMed
TargetP2X purinoceptor 4(RAT)
Max-Planck Institute for Experimental Medicine

Curated by PDSP Ki Database
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of inward ion current elicited by ATP at rat P2X4 receptor (wild type)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed