null

SMILES C[C@H](Nc1nc2ccc(cc2s1)-c1ccn(CC2CC2)c(=O)c1)C1CCOCC1

InChI Key InChIKey=WTFBXXYMHMHBJI-HNNXBMFYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107255   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

LigandBDBM50107255(CHEMBL3600783)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plu...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DKRPubMed