null

SMILES COc1ccc(cn1)-c1ccc2nc(N)sc2c1

InChI Key InChIKey=CBBGVZCNBLEQID-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333219   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

LigandBDBM50333219(6-(6-methoxypyridin-3-yl)benzo[d]thiazol-2-amine |...)copy SMILEScopy InChI

Affinity DataIC50: 794nMAssay Description:Inhibition of PI3Kalpha (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plu...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DKRPubMed

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

LigandBDBM50333219(6-(6-methoxypyridin-3-yl)benzo[d]thiazol-2-amine |...)copy SMILEScopy InChI

Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human p110alpha PI3K fragment by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q298878PPubMed