null

SMILES CS(=O)(=O)C1(CCOCC1)c1cc(nc(n1)-c1cccc2[nH]ccc12)N1CCOCC1

InChI Key InChIKey=FMFDMLOLARMKOL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427320   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

LigandBDBM50427320(CHEMBL2325705)copy SMILEScopy InChI

Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PI3Kalpha-mediated AKT phosphorylation at threonine 308 in human BT474 cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5Q5CPubMed