null

SMILES C[C@@H]1CCC[C@H](N2CCC(=CC2=O)c2c(F)ccc(Cl)c2F)c2cc(ccn2)-c2ccc(NC(=O)OCCOC(C)(C)C)cc2NC1=O

InChI Key InChIKey=URTZZBQNKCNCOJ-DFXYEROKSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241421   

TargetPlasma kallikrein(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM241421(US9409908, 53 | US9951071, Example 53)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Plasma kallikrein determinations were made in 0.1 M sodium phosphate buffer at a pH of 7.5 containing 0.1-0.2 M sodium chloride and 0.5% PEG 8000. De...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM241421(US9409908, 53 | US9951071, Example 53)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -12.3kcal/moleT: 2°CAssay Description:Plasma kallikrein determinations were made in 0.1 M sodium phosphate buffer at a pH of 7.5 containing 0.1-0.2 M sodium chloride and 0.5% PEG 8000. De...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27943K8US Patent