null

SMILES Cn1cc(cn1)-c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12

InChI Key InChIKey=SAWHJBBSBAZMKT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 291832   

TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291832(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 11.3nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291832(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291832(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 15.9nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent