null

SMILES FCCCN1CC(C1)Nc1ccc(nc1)[C@H]1N(CC(F)F)[C@@H](Cc2c1ccc1[nH]ncc21)C(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300985   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM300985(6-((6S,8S)-7- (2,2- difluoroethyl)- 8- (difluorome...)copy SMILES
Affinity DataIC50: 9.10E+3nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55QJ9US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM300985(6-((6S,8S)-7- (2,2- difluoroethyl)- 8- (difluorome...)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4SX5US Patent