null
SMILES CC1(C)CN(CC[C@@H]1C(=O)N[C@H]1CCC[C@H](CO)C1)c1ccc(cc1)C(F)(F)F
InChI Key InChIKey=APFUSSJGZAJSNI-VDZJLULYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50194140
Affinity DataIC50: 3nMAssay Description:Inhibition of human mPGES-1 expressed in 293E cells assessed as reduction in conversion of PGH2 to PGE2 after 1.5 min by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of mPGES-1 in human whole blood assessed as reduction in LPS-induced PGE2 production preincubated for 30 mins followed by LPS stimulation ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in recombinant human interleukin-1 beta-induced PGE2 production preincubated for 30 m...More data for this Ligand-Target Pair