null
SMILES CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12
InChI Key InChIKey=CBVCZFGXHXORBI-PXQQMZJSSA-N
PDB links: 15 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50067593
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Inhibition of wild-type HIV1 BH10 protease expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli by fluorometric assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.520nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.540nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.739nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKd: 1.20nMAssay Description:Binding affinity to Human immunodeficiency virus 1 protease by SPR biosensor interaction analysis at pH 7.4More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKd: 1.40nMAssay Description:Binding affinity to Human immunodeficiency virus 1 protease by SPR biosensor interaction analysis at pH 5.1More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKd: 5.5nMAssay Description:Binding affinity to Human immunodeficiency virus 1 protease by SPR biosensor interaction analysis at pH 4.1More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 0.880nMT: 2°CAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli incubated for 20 to 30 mins at room temperature using (Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-I...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 recombinant proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of wild type HIV1 NL4-3 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of purified HIV-1 protease using [Arg-Glu(EDANS)-Ser-Gin-Asn-Tyr-Ile-Val-Gin-Lys(dabcyl)-Arg) as fluorogenic substrate by fluorescence ass...More data for this Ligand-Target Pair