null
SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4cccnn34)cc2C(F)(F)F)CC1
InChI Key InChIKey=PHXJVRSECIGDHY-UHFFFAOYSA-N
PDB links: 15 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50322535
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of RET (unknown origin) V804 mutantMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant RET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)
Curated by ChEMBL