null
SMILES CN1C(=O)N[C@H](Cc2c[nH]c3c(Cl)cccc23)C1=O
InChI Key InChIKey=WIKGAEMMNQTUGL-SNVBAGLBSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 36372
Affinity DataEC50: 18nMpH: 7.3 T: 2°CAssay Description:In vitro kinase assay using RIP1More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of Flag-tagged human RIP1 (1 to 324 residues) after 30 mins by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human RIP1 in human U937 cells assessed as inhibition of TNF/zVAD.fmk induced necroptosis after 24 hrs by Cell titer-Glo luminescence a...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human RIP1 (1 to 375 residues) after 4 hrs by ADP-Glo reagent based assayMore data for this Ligand-Target Pair