null

SMILES C[C@H]1CC[C@@H](CC1)n1c2cnccc2c2cnc(Nc3ccc4CN(CCCO)CCc4n3)nc12

InChI Key InChIKey=ZZXOJMDHTLVJPY-KESTWPANSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112463   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Amgen Inc.

US Patent
LigandPNGBDBM112463(US8623885, 4)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.6Assay Description:The FLT3 inhibitory activity of the CDK4/6-FLT3 inhibitors was determined with a HTRF kinase assay. The FLT3 enzyme (GST-FLT3 fusion) was purchased f...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ06Z1US Patent