null

SMILES CCn1c(nc2cncc(C(=O)N3CC[C@H](N)C3)c12)-c1nonc1N

InChI Key InChIKey=PHWHNHYZZNJPLB-QMMMGPOBSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50365218   

TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50365218(CHEMBL1956071 | GSK screening, 29)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50365218(CHEMBL1956071 | GSK screening, 29)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human recombinant N-terminal his-tagged ROCK1 (3-543) expressed in baculovirus infected Sf9 cells using Biotin-Ahx-AKRRLSSLRA-CONH2 sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1KBVPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50365218(CHEMBL1956071 | GSK screening, 29)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Inhibition of N-terminal His-tagged human ROCK1 (3 to 543 residues) expressed in baculovirus infected Sf9 cells using biotin-Ahx-AKRRRLSSLRA-CONH2 as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82DN1PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50365218(CHEMBL1956071 | GSK screening, 29)copy SMILEScopy InChI
Affinity DataIC50: 39nMMore data for this Ligand-Target Pair
In DepthDetails
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50365218(CHEMBL1956071 | GSK screening, 29)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54VVPubMed