null

SMILES Cc1ccc(cc1-c1ccnc(c1)N1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=LZHLFLLBTSFGEX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202717   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM202717(US10245267, Example 63 | US10709712, Example 63 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.55nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1QXTUS Patent