null
SMILES NC1=NC(=O)C(N1)=C1CCNC(=O)c2[nH]ccc12
InChI Key InChIKey=JYRJOQGKGMHTOO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 16591
Affinity DataKi: 659nM ΔG°: -8.57kcal/molepH: 7.5 T: 2°CAssay Description:For Ki determinations a matrix of inhibitor and substrate concentrations were tested. Inhibitor concentrations were tested from four times IC50 with ...More data for this Ligand-Target Pair
Affinity DataIC50: 725nMAssay Description:In vitro inhibitory concentration against checkpoint kinase 1 (Chk1) by using [gamma-33P]-ATP] as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 353nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor compound in the presence ATP/[gamma-33P] ATP. 33P ...More data for this Ligand-Target Pair