null

SMILES FC(F)(F)c1cccc(c1)-c1ccc(Oc2ccc(cc2C#N)S(=O)(=O)Nc2ncns2)c(c1)-c1ccnc(CNCCC2CCNCC2)c1

InChI Key InChIKey=WSPHMGORSRQULF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50451447   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50451447(CHEMBL4217988)copy SMILEScopy InChI
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells by patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4ZN1PubMed
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50451447(CHEMBL4217988)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of mouse Nav1.7 expressed in HEK cells by patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4ZN1PubMed
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50451447(CHEMBL4217988)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK cells by patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4ZN1PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50451447(CHEMBL4217988)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells by automated patchXpress electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4ZN1PubMed
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50451447(CHEMBL4217988)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50451447(CHEMBL4217988)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of mouse Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed