null

SMILES NCCCC(O)=O

InChI Key InChIKey=BTCSSZJGUNDROE-UHFFFAOYSA-N

PDB links: 80 PDB IDs match this monomer. 551 PDB IDs contain this monomer as substructures. 551 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 24183   

TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P849XXPubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)copy SMILEScopy InChI
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of mouse GAT2-mediated [3H]GABA uptake expressed in human HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CWJPubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)copy SMILEScopy InChI
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of mouse GAT2 expressed in HEK cells assessed as inhibition of [3H]-GABA uptake after 25 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N269CPubMed
TargetSodium- and chloride-dependent GABA transporter 2(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human GAT2 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2222HPubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)copy SMILEScopy InChI
Affinity DataIC50: 7.08E+3nMAssay Description:Inhibition of mouse GTA 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2MJJPubMed