null

SMILES CN(C)CC1(CCC(F)CC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=OISBYAXPTPVNIZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 433673   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433673(US10562878, Compound 254 | US10562878, Compound 26...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433673(US10562878, Compound 254 | US10562878, Compound 26...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433673(US10562878, Compound 254 | US10562878, Compound 26...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Quantification of dopamine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat striatum. The uptake of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent