null

SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1

InChI Key InChIKey=VHGCDTVCOLNTBX-QGZVFWFLSA-N

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50366567   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataKi:  708nMAssay Description:Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0JWZPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of [3H]- DA reuptake into rat striatal synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76D26PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataKi:  1.45E+3nMAssay Description:Ability to inhibit reuptake of dopamine ([3H]DA) at dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26110WVPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S183BVPubMedDrugBank
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of 3,4-[ring-2,5,6-3H]dihydroxyphenylethylamine from human cloned DAT expressed in HEK293 cells by microplate scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41SCGPubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75H8VPubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of dopamine uptake at human DAT in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154J4PubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5FTKPubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataKd:  1.08E+3nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76D26PubMedDrugBank