null
SMILES COc1ccc(F)cc1CCCC1CCC(CCN)O1
InChI Key InChIKey=KFFYQORCJDVDTB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 30132
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute
Curated by ChEMBL
Human BioMolecular Research Institute
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute
Curated by ChEMBL
Human BioMolecular Research Institute
Curated by ChEMBL
Affinity DataKi: 1.10nM ΔG°: -12.1kcal/mole EC50: 2.30nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute
Curated by ChEMBL
Human BioMolecular Research Institute
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute
Curated by ChEMBL
Human BioMolecular Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute
Curated by ChEMBL
Human BioMolecular Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair