null

SMILES CNCC1(CCC(C)(O)CC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=IEEXXKGDHWBIJX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 433764   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433764(US10562878, Compound 273 | US10562878, Compound 27...)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433764(US10562878, Compound 273 | US10562878, Compound 27...)copy SMILEScopy InChI
Affinity DataIC50: 809nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433764(US10562878, Compound 273 | US10562878, Compound 27...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433764(US10562878, Compound 273 | US10562878, Compound 27...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433764(US10562878, Compound 273 | US10562878, Compound 27...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433764(US10562878, Compound 273 | US10562878, Compound 27...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent