null

SMILES COC(=O)C1C2CC[C@H](C[C@@H]1c1ccc(I)cc1)N2C

InChI Key InChIKey=SIIICDNNMDMWCI-LMRVLLHPSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50005576   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T3JPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc.

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Binding affinity of [3H]citalopram for serotonin transporter in monkeyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90992PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60PQ2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T3JPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc.

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Compounds binding ability to serotonin transporter was evaluated by displacing [3H]-paroxetine in baboon brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7TQDPubMed